Melanoma Incidence and Mortality Trends Among Patients Aged 59 Years or Younger in Sweden
Clinical Summary
View sourceWhat was studied
A national registry cohort of all primary invasive cutaneous melanomas in Sweden from 1990–2022 (>99% coverage) examined age-specific incidence and mortality trends, focusing on people younger than 60 years, using joinpoint regression.
Key findings
There were 34,800 melanomas in 33,324 individuals younger than 60 years (56.3% female; median age 48). Incidence rose steadily in ages 50–59; in ages 20–49 it peaked in 2013–2015 then stabilized or declined through 2022; incidence in those <20 stayed low without trends. Melanoma mortality fell significantly in ages 30–59 but not in those ≥60.
Study limitations
The study did not evaluate reasons for the incidence and mortality declines (e.g., UV protection, campaigns, demographics, treatments). Absolute rate changes and AAPCs are not reported in the provided text; joinpoint results are referenced but not detailed here.
Clinical implications
In Sweden, melanoma incidence and mortality have recently fallen in adults 30–49, while incidence continues to rise in those 50–59 and mortality has not fallen in ≥60. Maintain vigilance and prevention efforts, with particular attention to patients in their 50s and older.
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