Successful treatment of keratoacanthoma-like atypical squamous proliferations on the lower legs of elderly patients with intralesional triamcinolone suggests a unique reactive pathogenesis and response to therapy that differs from conventional squamous cell carcinoma
Journal of the American Academy of Dermatology
Clinical Summary
View sourceWhat was studied
Report of elderly patients with keratoacanthoma-like atypical squamous proliferations on the lower legs treated with intralesional triamcinolone, noting a response pattern distinct from conventional cutaneous squamous cell carcinoma.
Clinical implications
In older patients with keratoacanthoma-like atypical squamous proliferations of the lower legs, intralesional triamcinolone achieved clinical success in this report and may indicate a reactive process different from SCC; consider this when forming the diagnostic and management plan.
Related Questions
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How effective are intralesional corticosteroids (triamcinolone) for keratoacanthoma-like atypical squamous proliferations in older adults?How do keratoacanthoma-like atypical squamous proliferations differ from conventional cutaneous SCC in pathology and management?How do keratoacanthoma-like atypical squamous proliferations differ clinically and histologically from conventional cutaneous squamous cell carcinoma?What evidence supports intralesional triamcinolone for keratoacanthoma or KA-like lesions on the lower legs of older adults?What are evidence-based treatment options for lower-leg keratoacanthoma variants in elderly patients, and when is surgery preferred over medical therapy?Which histopathologic and clinical features help distinguish KA-like atypical squamous proliferations from SCC to guide treatment?